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Strategically,
the company aims to combine technology with pharmaceuticals
or human bio molecules in order to offer to the marketplace
a unique and patented dosage form. The starting point
to the business is a bank of available, patented and
toxicologically acceptable technology. The uniqueness
may be demonstrated in some of the following ways: the
reduction of adverse effects, more precise targeting
of the active constituent, the elimination of undesirable
blood level concentrations, enhanced compliance and
an accessibility to other indications.
The company operates in two ways and in both cases we
draw on our technology in order to develop a unique
dosage form. According to the first approach, CT identifies
the market opportunity and funds the pre-clinical and
early clinical investigations. However, the company
will also seek partners with a commercial interest in
specific product developments. These partners will generally
finance the development effort, with CT retaining the
rights to manufacture and supply the product for clinical
trials and to the market.
If the development of a product has been funded by CT
according to the first approach, the company would seek
to establish marketing agreements as soon as clinical
results provide clear evidence of future commercial
success. As an example, our dinoprostone controlled
release vaginal pessary was licensed to Forest Laboratories
of New York for marketing as Cervidil® in the USA.
Ferring NV was appointed as market partner for the EU
and South Africa, using the trademark Propess® whilst
they use the Cervidil® trademark in Canada. Manufacture
of the product takes place at East Kilbride and the
sales revenue is shared according to an agreed formula.
Alternatively,
where a partner company funds the product development
from the outset through milestone payments, based on
the partners own or selected active component,
the partner maintains the marketing rights for all or
selected territories according to the terms of the agreement.
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