KING OF PRUSSIA, PA, April 3, 2003 - Cytokine PharmaSciences, Inc. (CPSI) has signed an exclusive license with Integrity Pharmaceutical Corporation for U.S. rights to market CPSI's second-generation cervical ripening product. Cervical ripening agents are used as a first step in the induction of labor when a woman is at or past her delivery date. Through the agreement, CPSI will receive an up-front payment, milestones and royalties. CPSI will manage all pre-NDA clinical work; Integrity will share expenses for this work.

The cervical ripening product was developed by CPSI's wholly-owned Scottish subsidiary, Controlled Therapeutics (Scotland) Limited (CTS). CTS will also manufacture and supply the product to Integrity.

"Integrity is an innovative company committed to women's health," stated Denny Willson, CPSI president and CEO. "We are excited to be working with Integrity and are confident of their expertise to market our product successfully."

"Cytokine has a history of developing leading-edge technology, and we are pleased to partner with them in bringing this new cervical ripening product to women and their doctors," said Terri Pascarelli, president of Integrity Pharmaceutical. "The addition of this product to our portfolio will help us advance our goal to provide excellent health care for women and new treatment options for their physicians."

Company Information
CPSI (www.cytokinepharmasciences.com) is a private biopharmaceutical development company in King of Prussia, Pennsylvania, a suburb of Philadelphia. The company licenses technologies from academia and other sources, develops products with those technologies and sublicenses the products to third parties. Its product for cervical ripening is based upon a patented vaginal delivery system that uses a controlled-release polymer licensed from BTG, plc, a U.K. technology transfer company.

CTS (www.ctscotland.com) specializes in drug delivery technology and developed, among other products, the leading cervical ripening agent sold by Forest Laboratories in the United States under the name Cervidil® and in other parts of the world under the name Propess®. CTS currently employs 52 people at its state-of-the-art facility located in East Kilbride (near Glasgow) Scotland.

Integrity Pharmaceutical Corporation (www.integritypharma.com) is a private, fully integrated pharmaceutical company dedicated to providing innovative products for the Obstetric/Gynecology and Urology specialties. The company, located near Indianapolis, Indiana, currently markets numerous products through its nationwide sales force, including Duet by StuartNatal, StuartNatal® Plus 3™ and Stuart Prenatal.

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